CHARM Therapeutics

Charm Therapeutics designs and develops a new generation of small-molecule therapeutics that target the interaction between menin and the KMT2A protein, a key driver of acute myeloid leukemia (AML), using its proprietary AI-powered platform called DragonFold. The company’s lead program is a menin inhibitor optimized to maintain activity against all known clinical resistance mutations while minimizing safety and drug-interaction risks. Charm Therapeutics employs protein-ligand co-folding intelligence to inform molecular design, advancing its pipeline from preclinical stages toward the clinic.

Domain

charmtx.com

Employees

11-50

Last Funding

$80.0M

Founded

2020

Frequently Asked Questions

What technologies does CHARM Therapeutics use?+

CHARM Therapeutics uses 20 technologies including GDPR Cookie Consent Plugin by Webtoffee, Google Analytics, Google Tag Manager.

What industry is CHARM Therapeutics in?+

CHARM Therapeutics operates in the Artificial Intelligence (AI) industry.

Where is CHARM Therapeutics based?+

CHARM Therapeutics is headquartered in United Kingdom.

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Data last updated: June 2026