Tr1x

Tr1X is a biotechnology company that specializes in the development of allogeneic engineered regulatory T (Treg) and chimeric antigen receptor Treg (CAR-Treg) cell therapies aimed at treating autoimmune and inflammatory diseases. Tr1X's lead investigational therapy, TRX103, is an allogeneic engineered T cell product derived from CD4+ cells sourced from healthy donors, designed to mimic the function of Type 1 regulatory T (Tr1) cells. The U.S. Food and Drug Administration (FDA) has cleared the Investigational New Drug (IND) application for TRX103, allowing the initiation of clinical trials for treatment-refractory Crohn’s Disease. Additionally, Tr1X has received an $8 million grant from the California Institute for Regenerative Medicine (CIRM) to support the TRX103 Phase 1/2a clinical trial for Graft-Versus-Host Disease.

Domain

tr1x.bio

Employees

11-50

Last Funding

$50.0M

Founded

2017

Frequently Asked Questions

What technologies does Tr1x use?+

Tr1x uses 29 technologies including Cookiebot, Elementor, jsDelivr.

What industry is Tr1x in?+

Tr1x operates in the Biotechnology industry.

Where is Tr1x based?+

Tr1x is headquartered in United States.

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Data last updated: June 2026